Yes, the selected video wired input (HDMI 1, HDMI 2, USB-C) will be able to manage up until two different USB peripherals plugged to the 3.0 USB type A ports labeled as “Device 1” y “Device 2”. When using HDMI1 and HDMI 2 inputs, the computers that want to control this USB devices will also have to be plugged in the “Host 1” y “Host 2” 3.0 USB type B ports in order to control them. USB-C input doesn’t need any additional connection. Check the image by clicking here.